A buddy of mine runs the Windows Incident Response blog over at http://windowsir.blogspot.com/. He is always digging up something interesting and pertinent to all your Win32 system administrators; regardless of whether you use Perl or not.

And if this stuff interests (or scares the Hell out of) you then you should have a look at his books, Windows Forensics and Incident Recovery (http://www.windows-ir.com/); it received a great review on Slashdot (http://books.slashdot.org/article.pl?sid=04/11/09/202220).